KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K15
All Species:
17.27
Human Site:
S557
Identified Species:
47.5
UniProt:
Q6ZN16
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN16
NP_001001671.2
1313
147437
S557
E
A
E
E
R
T
V
S
L
W
H
V
S
P
T
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
S588
E
V
E
E
K
T
I
S
I
W
H
V
L
P
D
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
T554
T
D
P
V
S
T
V
T
L
S
L
L
E
P
E
Dog
Lupus familis
XP_548885
1422
158482
S653
E
A
E
E
K
T
V
S
L
W
H
V
S
P
T
Cat
Felis silvestris
Mouse
Mus musculus
A2AQW0
1331
149309
S561
E
A
E
E
R
T
V
S
L
W
H
V
S
P
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514080
1407
157705
P629
S
I
V
D
V
F
D
P
E
K
V
N
L
G
I
Chicken
Gallus gallus
XP_419725
1260
143069
F509
K
F
E
E
R
C
C
F
L
Y
V
L
H
N
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
T574
N
K
D
A
E
E
N
T
L
S
I
W
H
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
S515
E
W
L
F
N
L
S
S
I
K
G
V
S
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
44.2
81.6
N.A.
86
N.A.
N.A.
70.8
57.3
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
72.6
60.9
86.4
N.A.
90.3
N.A.
N.A.
79.4
73.5
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
62.2
P-Site Identity:
100
60
26.6
93.3
N.A.
100
N.A.
N.A.
0
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
80
40
100
N.A.
100
N.A.
N.A.
6.6
53.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
12
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
12
0
0
12
0
0
0
0
0
0
0
12
% D
% Glu:
56
0
56
56
12
12
0
0
12
0
0
0
12
0
12
% E
% Phe:
0
12
0
12
0
12
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
45
0
23
0
0
% H
% Ile:
0
12
0
0
0
0
12
0
23
0
12
0
0
0
12
% I
% Lys:
12
12
0
0
23
0
0
0
0
23
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
12
0
0
67
0
12
23
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
12
0
12
0
0
0
0
12
0
12
0
% N
% Pro:
0
0
12
0
0
0
0
12
0
0
0
0
0
56
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
12
0
12
56
0
23
0
0
45
0
12
% S
% Thr:
12
0
0
0
0
56
0
23
0
0
0
0
0
12
45
% T
% Val:
0
12
12
12
12
0
45
0
0
0
23
56
0
12
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
45
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _